The Ramban Synagogue, is the second oldest active synagogue in the Old City of Jerusalem. In 1267, Rabbi Nachmanides and additional scholars founded the synagogue to serve the local Jewish community. The Jewish community quickly expanded due to the synagogue's active and prevalent presence. Today there are two Ramban Synagogues in Jerusalem.
Over the years, the building has been the home to the Sephardi community, was converted into a mosque after being confiscated by a Mufti, and was used as a flour mill and a cheese factory. Today it is used by the Ashkenazi community.
After the 1948 Arab–Israeli War, the building was destroyed by the Arab Legion. As a result of the 1967 Six-Day War, Jews regained access to the property, and 700 years after Nachmanides revived the ancient building, the synagogue was reopened.